Latest Longevity Research

NutritionSep 1

Reaching 90 without dementia doesn’t mean you’re in the clear

ScienceDaily AgingTier 2

Clinical TrialsSep 1

NRF2 Downregulation in Oligodendrocytes as a Contributing Cause of Cognitive Decline in Mice

Fight Aging!Tier 2

Clinical TrialsSep 1

Amyloid-β Seeding as a Basis for a Blood Test for Alzheimer's Disease

Fight Aging!Tier 2

Clinical TrialsSep 1

Author Correction: Activating mutations in <i>CSF1R</i> and additional receptor tyrosine kinases in histiocytic neoplasms

Nature MedicineTier 1

Clinical TrialsSep 1

Altered oligodendrocyte function promotes cognitive decline in aging

Nature MedicineTier 1

Clinical TrialsSep 1

Isthmin-2 is a first-trimester predictor of preeclampsia and fetal growth restriction

Nature MedicineTier 1

Clinical TrialsSep 1

Antifungal therapy improves microbiome dynamics in inflammatory bowel disease

Nature MedicineTier 1

Clinical TrialsSep 1

Atezolizumab in early triple-negative breast cancer: the randomized phase 3 NSABP B-59/GeparDouze trial

Nature MedicineTier 1

SleepSep 1

Novel Wasserstein distance-based sleep-activity regularity metrics from wearable data for healthy aging: J-HAS

npj AgingTier 1

BiomarkersSep 1

The disease burden and risk factors of age-related diseases in Southeast Asia, East Asia, and Oceania: an analysis of the Global Burden of Disease Study 2023

npj AgingTier 1

Clinical TrialsAug 31

What Can Be Learned About Aging Clocks from Existing Clinical Trial Data for Longevity Interventions?

Fight Aging!Tier 2

Clinical TrialsAug 31

Bacterial Lipoic Acid Protein Ligase A Improves Mammalian Mitochondrial Function and Health

Fight Aging!Tier 2

SenolyticsAug 31

Mistranslation Mutations in Flies Surprisingly Extend Life

Fight Aging!Tier 2

EpigeneticsAug 31

Multimorbidity patterns influence mobility disability prevention in frail older adults from the SPRINTT trial

Nature AgingTier 1

EpigeneticsAug 31

Mapping structural aging across human tissues reveals tissue-specific trajectories and coordinated deterioration

Nature AgingTier 1

Clinical TrialsAug 31

Short-term effects of combinations of heart failure therapies on blood pressure, kidney function and serum potassium

Nature MedicineTier 1

SenolyticsAug 30

Fight Aging! Newsletter, August 31st 2026

Fight Aging!Tier 2

Clinical TrialsAug 30

Eplontersen with and without background transthyretin stabilizers in transthyretin amyloid cardiomyopathy: secondary analysis of a phase 3, randomized controlled trial

Nature MedicineTier 1

Clinical TrialsAug 30

Obesity medicines as disruptive innovation

Nature MedicineTier 1

NutritionAug 29

Dogs may hold surprising clues to human longevity

ScienceDaily AgingTier 2

SleepAug 29

Your sleep may be hiding an early clue to Alzheimer’s

ScienceDaily AgingTier 2

SupplementsAug 28

Physical Activity Correlates with Reductions in TMAO, Inflammation, and Harmful Bone Remodeling

Fight Aging!Tier 2

SupplementsAug 28

Senolytic Treatments Clear Harmful Senescent Microglia from the Aging Brain

Fight Aging!Tier 2

Clinical TrialsAug 28

MERKT is Involved in Enabling Microglia to Kill Motor Neurons in ALS

Fight Aging!Tier 2

EpigeneticsAug 28

Closing the gap in Alzheimer’s disease research through the Sex | Gender in Neurodegeneration Consortium

Nature AgingTier 1

EpigeneticsAug 28

Leaky oocytes propagate cGAS–STING signaling

Nature AgingTier 1

EpigeneticsAug 28

Mitochondrial DNA leakage in oocytes activates cGAS-STING signaling to drive ovarian aging

Nature AgingTier 1

BiomarkersAug 28

Aging-related transcriptomic signatures associated with recurrence following resection of stage I lung adenocarcinoma

npj AgingTier 1

SleepAug 27

Sleep bout length and nighttime activity predict longevity in medflies

npj AgingTier 1

NutritionAug 26

Scientists may have found a shortcut to calorie restriction’s anti-aging benefits

ScienceDaily AgingTier 2

NutritionAug 26

What you eat before age 2 may affect your health 70 years later

ScienceDaily AgingTier 2

EpigeneticsAug 26

Loss of cGAS disrupts H3K9me3 organization and derepresses LINE1 to cause inflammaging

Nature AgingTier 1

EpigeneticsAug 26

Contracting myografts mimic exercise response

Nature AgingTier 1

EpigeneticsAug 26

Cytotoxic CD4<sup>+</sup> T cells induce age-associated myelopoiesis through CCL5–CCR5 signaling

Nature AgingTier 1

BiomarkersAug 26

Sex differences in the prevalence and incidence of motoric cognitive risk syndrome: a systematic review and meta-analysis

npj AgingTier 1

BiomarkersAug 26

Space weather fluctuations and epigenetic aging in an elderly male cohort from Massachusetts, USA

npj AgingTier 1

NutritionAug 25

Shingles vaccine linked to 24% lower dementia risk

ScienceDaily AgingTier 2

BiomarkersAug 25

Independent associations of clonal hematopoiesis of indeterminate potential and mosaic Y loss with all-cause and cause-specific mortality in men

npj AgingTier 1

SleepAug 24

Too much or too little sleep may make your body age faster

ScienceDaily AgingTier 2

BiomarkersAug 24

Incidental findings from community-based mobile low-dose CT lung screening among older adults: a multicenter retrospective observational study in China

npj AgingTier 1

NutritionAug 23

A major Alzheimer’s risk gene may shrink brain cells years before symptoms

ScienceDaily AgingTier 2

SleepAug 23

This common vitamin was linked to 13% better cognitive scores

ScienceDaily AgingTier 2

NutritionAug 23

This shark can live 400 years. Its eyes barely seem to age

ScienceDaily AgingTier 2

NutritionAug 17

A little-known protein may be fueling Alzheimer’s — and scientists found a way to block it

ScienceDaily AgingTier 2

NutritionAug 16

A little movement in midlife could pay off for your brain years later

ScienceDaily AgingTier 2

BiomarkersAug 14

Women taking estrogen had fewer signs of Alzheimer’s in their brains

ScienceDaily AgingTier 2

NutritionAug 6

Nearly half of dementia cases may be linked to risks you can change

ScienceDaily AgingTier 2

SleepJul 31

Scientists discover why poor sleep may harm some brains more

ScienceDaily AgingTier 2

BiomarkersJul 31

A 42-year-old childhood obesity theory may be wrong

ScienceDaily AgingTier 2

SleepJul 31

AI can tell if your brain is aging faster than you are

ScienceDaily AgingTier 2

NutritionJul 26

A hidden Alzheimer’s tipping point may decide who gets dementia

ScienceDaily AgingTier 2

NutritionJul 25

Superagers keep youthful memories but their DNA does not explain why

ScienceDaily AgingTier 2

NutritionJul 24

APOE2 may protect the brain from Alzheimer’s and aging

ScienceDaily AgingTier 2