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PAST 100
The science of living past 100
Weekly longevity research read the way it should be — every claim links to the original paper. No affiliate links. No sponsored content. No conflicts of interest.
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Every factual claim in the Paper of the Week links to the original journal paper — not a press release, not a science blog, not a tweet. If we cannot source it, we do not publish it.
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Every study receives its context: was it in mice or humans? What was the sample size? Has it been replicated? We report effect sizes and confidence intervals, not just p-values.
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Retractions reported as prominently as findings
When longevity research fails to replicate or is retracted, we cover it. Bad news about a study we previously covered gets the same column inches as the original finding.
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Issue #1 · Paper of the Week
The Hallmarks of Aging — the 12 root causes, explained simply
What if the reason you age isn't one thing, but twelve interconnected processes all degrading simultaneously? In 2013, López-Otín and colleagues published what became the most cited framework in aging biology: the Hallmarks of Aging. Updated in 2023 to include three new hallmarks, the framework describes the cellular and molecular mechanisms that drive aging across all species studied to date. Understanding the hallmarks is the prerequisite for understanding almost every intervention discussed in longevity research.
Deep Dives + The Verdict for Premium members
Source
Cell · 2023 · López-Otín et al.
Evidence rating
Strong
Replicated, human, large sample
Reading time
8 min
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